
Last and First Men
Olaf Stapledon · 1930
A history of humanity across two billion years and eighteen successor species. Stapledon invented cosmic SF in 1930, and this novel remains the most audacious thought experiment in the genre's history. Clarke, Asimov, and Le Guin all cited it as a direct influence.
Science Fiction & Fantasy · the Pro canon
The case for it, the case against, and the rest of the canon open with Pro.